Fig 7. Antifungal activity of LMM11 against intracellular and extracellular C. krusei after phagocytosis by J774-A1 macrophages.

After 24 hours, supernatants were collected for the CFU determination of extracellular cells. Alternatively, macrophages were lysed for the CFU determination of intracellular cells. (LMM11) Macrophages with internalized C. krusei cells and incubated with LMM11 at concentration 32 μg/mL. (Control) Macrophages with internalized C. krusei cells and incubated with RPMI-1640 only (untreated). *p<0.05, statistically significant values comparing extracellular or intracellular treated versus extracellular or intracellular untreated. The bars indicate the standard deviation.