Table 3. Incidence of nausea, vomiting and PONV in the groups.
Variable | GI (%) (n = 40) | GII (%) (n = 40) | P (2 tailed) |
---|---|---|---|
Nausea | |||
0 to 1 h | 4 (10.0) | 3 (7.5) | 0.69 |
1 to 6 h | 1 (2.5) | 1 (2.5) | 1.00 |
6 to 24 h | 0 | 2 (5.0) | 1.00 |
24 to 48 h | 2 (5.0) | 5 (12.5) | 0.43 |
Overall 0 to 48 h | 6 (15.0) | 11 (27.5) | 0.17 |
Vomiting | |||
0 to 1 h | 0 | 1 (2.5) | 0.3 |
1 to 6 h | 0 | 0 | 0 |
6 to 24 h | 0 | 0 | 0 |
24 to 48 h | 0 | 0 | 0 |
Overall 0 to 48 h | 0 | 1 (2.5) | 0.3 |
PONV | |||
0 to 1 h | 4 (10.0) | 3 (7.5) | 0.69 |
1 to 6 h | 1 (2.5) | 1 (2.5) | 1.00 |
6 to 24 h | 0 | 2 (5.0) | 1.00 |
24 to 48 h | 2 (5.0) | 5 (12.5) | 0.43 |
Overall 0 to 48 h | 6 (15.0) | 11 (27.5) | 0.17 |
Data are the numbers (%). GI: palonosetron 1 μg kg-1; GII: palonosetron 75 μg; PONV: postoperative nausea and vomiting; % percentage. The statistical calculator MedCal was used using GI and GII and corresponding sample size proportion.