Author response table 2. Performance of Me-RIP/m6A seq, EpiNano and Nanopore differential error rate methods using S.cerevisiae MAZTER-seq sites as the “ground truth”.

	Me-RIP seq	Me-RIP seq motifs	Me-RIP seq motifs (ACA)	EpiNano p >= 0.5	Nanopore error sites	Nanopore error site motifs	Nanopore error site motifs (ACA)
Total ground truth sites	1,257	1,257	1,257	1,257	1,257	1,257	1,257
Total prediction sites	1,100	669	361	8,012	2,294	555	348
Ground truth sites supported	131	95	95	0	123	116	116
Unsupported prediction sites	973	575	267	8,012	2,130	442	235
Unsupported ground truth sites	1,126	1,162	1,162	1,257	1,134	1,141	1,141
Precision	0.119	0.142	0.262	0	0.055	0.208	0.330
Recall	0.104	0.076	0.076	0	0.098	0.092	0.092
F1 score	0.111	0.099	0.117	0	0.070	0.128	0.144
Fisher p value	1.7E-124	2.6E-155	1.9E-183	1	8.5E-143	6.93E-211	4.26E-238