Table 3.

Summary of one-way sensitivity analyses conducted and optimal strategy based on WTP of £20 000

Parameter	Change	Optimal strategy
Cost of RDC	Change number of patients per day from 2.78 to 5	RDC (outperforms)
Cost of RDC	Change number of patients per day from 2.78 to 4	RDC (outperforms)
Cost of RDC	Change number of patients per day from 2.78 to 3	No RDC (ICER = £22 140)
Cost of RDC	Change number of patients per day from 2.78 to 2	No RDC (ICER = £69 969)
Cost of RDC	Change number of patients per day from 2.78 to 1	No RDC (ICER = £213 459)
All costs	Add 20% to all costs	No RDC (ICER = £35 678)
All costs	Subtract 20% from all costs	No RDC (ICER = £23 786)
All costs	Add 50% to all costs	No RDC (ICER = £44 598)
All costs	Subtract 50% from all costs	RDC (ICER = £14 866)
Adjusted OR for control group cancer patients	After 2 months increase cancer QALY OR from 0.69 to 0.95	No RDC (ICER = £34 848)
Cancer diagnosis utility	Utility decreases by 3% to 0.602	No RDC (ICER = £62 637)
Utility	Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis	No RDC (ICER = £245 102)
Utility	Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 5 per day	RDC (outperforms)
Utility	Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 4 per day	RDC (outperforms)
Utility	Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 3 per day	No RDC (£182 514)
Utility	Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 2 per day	No RDC (ICER = £576 811)
Utility	Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 1 per day	No RDC (ICER = £1 759 700)

ICER = incremental cost-effectiveness ratio. OR = odds ratio. QALY = quality-adjusted life year. RDC = rapid diagnosis centre. WTP = willingness-to-pay.