Table 3.
Multivariate analysis using Cox proportional hazard model, n (%)
| Characteristics | n | Median OS (mo) | 1-yr survival | 2-yr survival | 3-yr survival | P value |
| Sex | 0.031 | |||||
| Female | 4 | 10.5 | 2 (50.0) | 1 (25.0) | 0 | |
| Male | 42 | 34.5 | 31 (73.8) | 27 (64.3) | 23 (54.5) | |
| Age (yr) | 0.264 | |||||
| ≤ 60 | 37 | 34 | 26 (70.3) | 22 (59.5) | 20 (54.1) | |
| > 60 | 9 | 35 | 7 (77.8) | 6 (66.7) | 4 (44.4) | |
| BCLC staging | 0.657 | |||||
| B | 10 | 37.5 | 8 (80.0) | 8 (80.0) | 7 (70.0) | |
| C | 36 | 30 | 25 (69.4) | 20 (55.6) | 17 (47.2) | |
| Size of tumor (cm) | 0.300 | |||||
| 8-10 | 23 | 34 | 18 (78.3) | 14 (60.9) | 12 (51.4) | |
| > 10 | 23 | 26 | 15 (65.2) | 14 (60.9) | 12 (52.2) | |
| No. of tumors | 0.087 | |||||
| Single | 35 | 34 | 26 (74.3) | 23 (65.7) | 20 (56.7) | |
| Multiple | 11 | 19 | 7 (63.6) | 5 (54.5) | 4 (36.4) | |
| Child–Pugh class | 0.640 | |||||
| A | 45 | 34 | 32 (77.8) | 28 (62.2) | 24 (53.3) | |
| B | 1 | 19 | 1 (100) | 0 | 0 | |
| Pseudocapsule | 0.289 | |||||
| Yes | 11 | 44 | 10 (90.9) | 9 (81.8) | 7 (63.6) | |
| No | 35 | 30 | 23 (65.7) | 19 (54.3) | 17 (48.2) | |
| Vascular invasion | 0.019 | |||||
| Yes | 4 | 8 | 1 (25.0) | 1 (25.0) | 0 | |
| No | 42 | 34.5 | 32 (76.2) | 27 (64.3) | 24 (56.8) | |
| AFP positive1 | 0.051 | |||||
| Yes | 17 | 14.5 | 9 (52.9) | 6 (35.3) | 6 (35.3) | |
| No | 29 | 35 | 24 (79.3) | 22 (75.9) | 18 (61.4) |
1
AFP ≥ 200 ng/mL. BCLC: Barcelona Clinic Liver Cancer; OS: Overall survival; AFP: α-fetoprotein.