Table 3.
Comparison of rates of change after adjusting for age at enrollment for outcomes in participants who developed antibodies compared to those who did not
| Outcome | N obs, N | ADA+ minus ADA− (95% CI) |
p value |
|---|---|---|---|
| 6MWT, m | 46, 10 | −14.35 (−27.91, −0.79) | 0.038 |
| Left shoulder flexion, ° | 45, 10 | 1.11 (0.14, 2.07) | 0.024 |
| Right shoulder flexion, ° | 45, 10 | 1.06 (−0.08, 2.19) | 0.068 |
| Left elbow extension, ° | 41, 10 | 0.07 (−0.43, 0.57) | 0.779 |
| Right elbow extension, ° | 41, 10 | 0.01 (−0.48, 0.51) | 0.959 |
| Left hip extension, ° | 46, 10 | 0.28 (−0.39, 0.96) | 0.407 |
| Right hip extension, ° | 46, 10 | 0.56 (−0.19, 1.31) | 0.144 |
| Max HR treadmill, bpm | 43, 10 | 0.16 (−0.79, 1.11) | 0.744 |
| Time on treadmill, min | 38, 10 | −0.11 (−0.43, 0.22) | 0.517 |
| Handgrip, kg | 45, 10 | 0.01 (−0.18, 0.19) | 0.944 |
| Peak torque at 90°/s, Ft-lbs/100 lbs | 38, 10 | −0.27 (−0.82, 0.27) | 0.322 |
| Peak torque at 120°/s, Ft-lbs/100 lbs | 38, 10 | −0.16 (−0.66, 0.33) | 0.524 |
| Sitting height, cm | 37, 10 | −0.07 (−0.18, 0.04) | 0.195 |
| Arm span, cm | 38, 10 | −0.06 (−0.35, 0.23) | 0.680 |
| Standing height, cm | 40, 10 | 0.01 (−0.18, 0.21) | 0.884 |
| Height SDS | 40, 10 | 0.00 (−0.02, 0.03) | 0.904 |
A negative coefficient means antibody positive participants had a more negative change in the outcome after adjustment for age at enrollment compared to antibody negative participants
Statistically significant p-values are bold <0.05