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. 2020 Jan 8;10:1346. doi: 10.3389/fneur.2019.01346

Table 5.

Brain age prediction results reported in literatures.

Articles Modalties Input data Methods Subjects (Age range) r MAE R2
Cole et al. (21) sMRI GM+WM volumes GPR 2001 NC (18–90) 0.94 5.02 0.88
Cole et al. (25) sMRI GM volume map
Raw MRI map
CNN 2001 NC (18–90) 0.96 0.94 4.16 4.65 0.92 0.88
Franke et al. (17) sMRI GM+WM volumes RVR 394 NC (5–18) 0.93 1.10 -
Franke et al. (16) sMRI GM volume RVM 655 NC (19–86) 0.92 5.00 -
Li et al. (40) rs-fMRI Functional connectivity CNN 983 NC (8–22) 0.61 2.15
Liem et al. (19) rs-fMRI + sMRI Functional connectivity;Structural measures SVR+RF 2354 NC (19–82) - 4.29 -
Lin et al. (23) DTI Topological network properties ANN 112 NC (50–79) 0.80 4.29 -
Valizadeh et al. (20) sMRI Anatomical feature sets SVM NN 3144 NC (7–96) - - 0.84 0.84

sMRI, Structural Magnetic Resonance Imaging; rs-fMRI, resting-state Functional Magnetic Resonance Imaging; DTI, Diffusion Tensor Imaging; GM, Gray Matter; WM, White matter; Raw MRI, rigid only registrated structural MRI; Structural measures: cortical thickness, cortical surface area, and subcortical volumes; Anatomical feature sets: cortical volume, thickness, area, subcortical volume, cerebellar volume, etc; GPR, Gaussian Process Regression; CNN, Convolutional Neural Network; RVR, Relevance Vector Regression; RVM, Relevance Vector Machine; SVR, Support Vector Regression; RF, Random Forest; ANN, Artificial Neural Network; SVM, Support Vector Machine; NN, Neural Network; NC, normal controls.