Table 1.
Serum concentrations reported for 3,5-T2 and 3,3′-T2 over the last 4 decades using different analytical techniques (immunoassay formats, mass spectrometry).
| References | Assay type | Serum 3,5-T2 (pM) | Serum 3,3′-T2 (pM) | Species |
|---|---|---|---|---|
| Richards et al. (23); Richards et al. (24); Richards et al. (25) | LC/MS-MS | <5 | 41 ± 8 | Human |
| Lehmphul et al. (20) | CLIA | 290 ± 10 | – | Human |
| Gu et al. (26) | LC/MS-MS | – | 52 ± 16 | Human |
| Jonklaas et al. (27) | LC/MS-MS | – | 12.2–28.2 | Human |
| Moreno et al. (28); Pinna et al. (29) | RIA | 4.6 ± 0.4 | 68 ± 21 | Rat |
| Pinna et al. (30) | RIA | 16.3 ± 6.4 | – | Human |
| Engler and Burger (31) | RIA | 7.6 ± 3.4 | – | Human |
| Jaedig and Faber (32) | RIA | 70 | 42 | Human |
| Kirkegaard et al. (33) | RIA | 105 ± 51 | 36 ± 15 | Human |
| Nishikawa et al. (34) | RIA | 196 ± 36 | 67 ± 36 | Human |
| Pangaro et al. (35) | RIA | 82 ± 4 | – | Human |
| Maciel et al. (36) | RIA | 139 ± 67 | – | Human |
| Meinhold and Schürnbrand (37) | RIA | 100 | – | Human |
Bold values give mean serum concentrations reported by authors.