Table 4.

SF-36 within-subjects pairwise comparisons; significance between successive time-points; *p < 0.05; **p < 0.01; ***p < 0.001.

	Estimated Marginal Means ± SE	Estimated Lower – Upper Bounds	Pairwise Comparison (p)
SF – Social activities
Baseline	33.54±4.23	25.02 – 42.05
3 months	41.11±4.29	32.47 – 49.75	0.021*
6 months	46.67±3.32	39.97 – 53.37	0.015*
9 months	53.01±3.23	46.50 – 59.53	<0.001***
12 months	56.28±3.11	50.02 – 62.54	0.074
SF – Physical pain
Baseline	41.93±5.15	31.55 – 52.32
3 months	40.47±4.85	30.70 – 50.24	0.544
6 months	46.43±5.55	35.26 – 57.61	0.051
9 months	50.22±4.83	40.48 – 59.96	0.041*
12 months	56.99±4.26	48.41 – 65.56	0.051
SF – Physical health
Baseline	28.77±5.08	18.54 – 38.99
3 months	36.93±5.94	24.97 – 48.89	0.068
6 months	43.80±5.19	33.34 – 54.26	0.021*
9 months	46.86±5.19	36.40 – 57.32	0.115
12 months	55.86±4.95	45.88 – 65.83	0.001**
SF – Emotional state
Baseline	18.41±5.70	6.96 – 29.90
3 months	21.15±6.16	8.75 – 33.55	0.359
6 months	34.85±5.75	23.26 – 46.43	0.001*
9 months	40.70±5.46	29.69 – 51.70	0.057
12 months	47.75±5.38	36.92 – 58.58	0.017*
SF – General health
Baseline	45.50±4.46	36.52 – 54.48
3 months	46.54±4.25	37.99 – 55.10	0.690
6 months	50.24±3.80	42.58 – 57.90	0.166
9 months	54.84±3.39	48.01 – 61.67	0.038*
12 months	58.62±3.44	51.69 – 65.56	0.101
SF – Mental health
Baseline	41.63±4.40	32.78 – 50.49
3 months	48.32±4.40	39.44 – 57.19	0.001**
6 months	50.58±3.80	42.93 – 58.23	0.291
9 months	56.00±3.41	49.13 – 62.87	0.001**
12 months	57.85±3.28	51.24 – 64.47	0.224
SF – Physical activity
Baseline	54.17±6.26	41.56 – 66.77
3 months	53.47±6.21	40.94 – 65.99	0.469
6 months	59.99±5.20	49.51 – 70.47	0.005**
9 months	61.74±4.88	51.92 – 71.57	0.182
12 months	64.65±4.58	55.42 – 73.88	0.223
SF – Vitality
Baseline	38.66±4.23	30.14 – 47.18
3 months	46.85±4.56	37.66 – 56.04	0.011*
6 months	51.11±4.38	42.29 – 59.94	0.038*
9 months	54.57±4.20	46.10 – 63.04	0.028*
12 months	57.95±4.03	49.84 – 66.07	0.086

SE, standard error; SF-36, Short Form Health Survey.