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. 2020 Jan 8;10:1263. doi: 10.3389/fgene.2019.01263

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Copyright © 2020 Xiao, Zhong, Liu, Ding, Guan, He, Pu, Jiang, Ma and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of differentially methylated regions (DMRs) in different categories. (A) Manhattan plot of DMRs in a chromosomal landscape. Dots above the dotted line presented DMRs with –log10 (p) > 20. The heatmap below the dots represents the density (counts) of the DMR distribution within chromosomes. The blue and red dots indicate the status of hypomethylation and hypermethylation in the D45 regions, respectively. (B) The filtration of differentially methylated genes and the number of DMRs in different genomic regions.