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. 2020 Jan 8;10:1263. doi: 10.3389/fgene.2019.01263

Figure 7.

Figure 7

The PDGFC gene affects human hair inner root sheath cell (HHIRSC) migration and proliferation by regulating hair follicle-related gene expression. (A) A wound healing assay was conducted after the transient transfection of PDGFC vectors or si-PDGFC. Wound closure was monitored after 12 h, and the calculation of the wound closure area is explained in the methods. The mean ± standard deviation (n = 3), *P < 0.05 (two-sided t-test). (B) The cell proliferation rate was evaluated at four time points using the Cell Counting Kit-8 assay after the corresponding cell treatments. The mean ± standard deviation (n = 3), *P < 0.05, (two-sided t-test). (C) Results from the quantitation of gene expression related to hair development by quantitative PCR in HHIRSCs at 48 h after transfection with control (scrambled) or the PDGFC vector or si-PDGFC. N = 3; *P < 0.05, **P <0.01 (two-sided t-test).