Table 4.

Gene mutation detection in urine supernatant and urine sediments

Supernatant	Cancer (n = 92)		Control (n = 33)		PPV (%)	NPV (%)
	n	Sensitivity (%)	n	Specificity (%)
TERT	42	46	0	100	100	40
FGFR3	35	38	0	100	100	37
TP53	27	29	0	100	100	34
PIK3CA	24	26	0	100	100	33
KRAS	15	16	0	100	100	30
CDKN2A	9	10	0	100	100	28
HRAS	9	10	0	100	100	28
AKT1	7	8	0	100	100	28
ERBB2	6	7	0	100	100	28
ACTB	4	4	1	97	80	27
BRAF	3	3	1	97	75	26
KDM6A	3	3	1	97	75	26
EGFR	2	2	0	100	100	27
CTNNB1	1	1	2	94	33	25
CUL1	1	1	0	100	100	27
FBXW7	1	1	0	100	100	27
PTEN	1	1	0	100	100	27
STAG2	1	1	0	100	100	27
U2AF1	1	1	1	97	50	26

Sediment	Cancer (n = 92)		Control (n = 33)		PPV (%)	NPV (%)
	n	Sensitivity (%)	n	Specificity (%)
TERT	44	48	0	100	100	41
FGFR3	34	37	1	97	97	36
PIK3CA	22	24	1	97	96	31
TP53	20	22	6	82	77	27
KRAS	14	15	0	100	100	30
HRAS	13	14	0	100	100	29
CDKN2A	9	10	0	100	100	28
AKT1	7	8	0	100	100	28
ERBB2	6	7	0	100	100	28
BRAF	3	3	0	100	100	27
KDM6A	2	2	0	100	100	27
CTNNB1	1	1	0	100	100	27
FBXW7	1	1	0	100	100	27
PTEN	1	1	0	100	100	27
STAG2	1	1	0	100	100	27

n: The number of samples in which the gene mutation was detected