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. 2020 Jan 18;11(1):36–46. doi: 10.5312/wjo.v11.i1.36

Table 7.

Characteristics of all patients with positive alpha-defensin lateral flow test and/or positive or inconclusive criteria

Case Criteria
A
B
C
D
E
F
G
H
I
PJI?
Art Sinus tract Visible purulence CRP (mg/ L) ESR (mm/h) WBC count (cells/μL) PMN% Culture synovial fluid (nr of cultures) Culture tissue (nr of cultures) AD MSIS (+/-; criteria) EBJIS (+/-; criteria) 2018 ICM (+/-/i; criteria) Revision surgery 1- or 2-stage
1 CoC - - 6.5 21.0 19100 91 neg (1) neg (6) + - E,F + E,F + E,F,I Yes 2-stage
2 MoP Yes - 9.0 23.0 - - pos (2) pos (8/9) + + A,G,H + A,G,H + A,G,H,I Yes 2-stage
3 MoP - - 8.5 29.0 3000 4 neg (2) - - - + E - No -
4 MoP - - 9.8 16.0 6200 77 neg (2) pos (5/8) + + E,H + E,F,H + E,H,I Yes 2-stage
5 CoC - - 6.9 10.0 2300 - neg (1) - - - + E - No -
6 MoP - - 12.0 26.0 10 - neg (2) pos (1/2) - - C,H - i C,H Yes 1-stage
7 MoP - - - - 9350 - neg (1) - - - E + E - E No -
8 HA - - - - - - neg (1) pos (1/6) + - H - i H,I Yes 1-stage
9 MoP - - 144.0 64.0 37300 92 pos (1/2) pos (2/6) + + C,D,E,F,G,H + E,F,G,H + C,D,E,F,H,I Yes DAIR
10 MoP - - 61.0 72.0 7900 95 pos (1/1) pos (9/9) + + C,D,E,F,G,H + E,F,G,H + C,D,E,F,H,I Yes 2-stage
11 MoP - - 71.0 55.0 35300 97 pos (2/2) pos (7/7) + + C,D,E,F,G,H + E,F,G,H + C,D,E,F,H,I Yes 2-stage
12 HA - - 9.6 - 4900 81 - - + - E,F + E,F + E,F,I No -
13 MoM - Yes 195.0 - 264000 96 neg (2) - + + B,C,E,F + B,E,F + B,C,E,F,I No -
14 MoP - - 15.0 13.0 8000 - neg (1) neg (6) + - C,E + E + C,E,I Yes 2-stage
15 HA - - 1.0 9.0 4000 15 neg (2) - - - E + E - E No -
16 MoM - - 5.7 8.0 5170 52 neg (3) - + - E + E + E,I No -

Art: Articulation; CoC: Ceramic on ceramic; MoP: Metal on polyethylene; MoM: Metal on metal; HA: Hemiarthroplasty; CoP: Ceramic on polyethylene; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; WBC: White blood cell; PMN%: Polymorphonuclear neutrophil percentage; PJI: Prosthetic joint infection; AD: Alpha-defensin test; MSIS: Musculoskeletal Infection Society; EBJIS: The European Bone and Joint Infection Society; i: Inconclusive; +: Positive; -: Negative.