Table 1. Comparison of Characteristics between Patients with 90-Day Catastrophic Outcome (mRS 4–6) and Those with Non-Catastrophic Outcome (mRS 0–3).
| Variables | Total (n = 82) | mRS 4–6 (n = 47) | mRS 0–3 (n = 35) | P |
|---|---|---|---|---|
| Age, yrs | 83 (81–86) | 82 (80–86) | 83 (81–86) | 0.524 |
| Age > 85 yrs | 22 (26.8) | 13 (27.7) | 9 (25.7) | 0.844 |
| Sex, female | 54 (65.9) | 34 (72.3) | 20 (57.1) | 0.151 |
| Risk factors | ||||
| Hypertension | 65 (79.3) | 38 (80.9) | 27 (77.1) | 0.682 |
| Diabetes mellitus | 21 (25.6) | 12 (25.5) | 9 (25.7) | 0.985 |
| Dyslipidemia | 20 (24.4) | 9 (19.1) | 11 (31.4) | 0.200 |
| Atrial fibrillation | 51 (62.2) | 31 (37.8) | 20 (57.1) | 0.416 |
| Smoking | 12 (14.6) | 10 (21.3) | 2 (5.7) | 0.062 |
| Coronary artery disease | 12 (14.6) | 6 (12.8) | 6 (17.1) | 0.579 |
| Previous stroke or TIA | 22 (26.8) | 12 (25.5) | 10 (28.6) | 0.759 |
| Congestive heart failure | 4 (4.9) | 2 (4.3) | 2 (5.7) | 1.000 |
| Intravenous thrombolysis | 35 (42.7) | 23 (48.9) | 12 (34.3) | 0.185 |
| Occlusion sites | 0.963 | |||
| MCA | 56 (68.3) | 32 (68.1) | 24 (68.6) | |
| ICA | 26 (31.7) | 15 (31.9) | 11 (31.4) | |
| DWI-ASPECTS | 7 (6–8) | 7 (5–8) | 8 (7–9) | 0.014 |
| DWI-ASPECTS ≥ 7 | 52 (63.4) | 25 (53.2) | 27 (77.1) | 0.026 |
| CT-ASPECTS | 9 (8–10) | 9 (8–9) | 9 (8–10) | 0.367 |
| Time to treatment, min | 210 (160–285) | 220 (165–285) | 195 (150–285) | 0.189 |
| Procedure time, min | 37 (25–53) | 42 (30–55) | 29 (20–50) | 0.031 |
| Time to final reperfusion, min | 257 (195–329) | 277 (203–332) | 227 (180–320) | 0.091 |
| Baseline NIHSS score | 15 (12–16) | 15 (12–18) | 15 (12–16) | 0.101 |
| Underlying severe ICAS | 6 (7.3) | 1 (2.1) | 5 (14.3) | 0.079 |
| Cervical ICA tandem occlusion | 11 (13.4) | 7 (14.9) | 4 (11.4) | 0.751 |
| Stroke etiology | 0.557 | |||
| Cardioembolism | 52 (63.4) | 32 (68.1) | 20 (57.1) | |
| Large artery atherosclerosis | 15 (18.3) | 8 (17.0) | 7 (20.0) | |
| Undetermined | 15 (18.3) | 7 (14.9) | 8 (22.9) | |
| Successful reperfusion | 61 (74.4) | 30 (63.8) | 31 (88.6) | 0.011 |
| Subarachnoid hemorrhage | 12 (14.6) | 8 (17.0) | 4 (11.4) | 0.543 |
| Hemorrhagic infarction | 16 (19.5) | 11 (23.4) | 5 (14.3) | 0.303 |
| Parenchymal hemorrhage | 5 (6.1) | 4 (8.5) | 1 (2.9) | 0.387 |
| Symptomatic hemorrhage | 3 (3.7) | 3 (6.4) | 0 | 0.257 |
Values are presented as n (%) or median (interquartile range). ASPECTS = Alberta stroke program early CT score, DWI = diffusion-weighted imaging, ICA = internal carotid artery, ICAS = intracranial atherosclerotic stenosis, MCA = middle cerebral artery, mRS = modified Rankin Scale, NIHSS = National Institutes of Health Stroke Scale, TIA = transient ischemic attack