. Author manuscript; available in PMC: 2021 Apr 1.

Published in final edited form as: Clin Gastroenterol Hepatol. 2019 Jul 15;18(4):830–837.e1. doi: 10.1016/j.cgh.2019.07.012

Table 1:

Lynch Syndrome Gastric Cancer Screening Recommendations and Guidelines from Various Professional Societies

Professional Society	Recommendations
American College of Gastroenterology (ACG)⁸	- Consider baseline EGD with biopsy for H. pylori for all Lynch syndrome carriers at age 30–35
	- Consider ongoing surveillance every 3–5 years for Lynch syndrome carriers with a family history of gastric or duodenal cancer
United States Multi-Society Task Force⁹	- Consider baseline EGD with biopsy for H. pylori for all Lynch syndrome carriers at age 30–35
	- Consider ongoing surveillance every 2–3 years based on individual patient risk factors
National Comprehensive Cancer Network (NCCN)¹⁰	- Consider EGD surveillance with H. pylori testing every 3–5 years for all Lynch syndrome carriers, beginning at age 40
	- Lynch syndrome carriers with a family history of gastric/small bowel cancer and those of Asian descent may benefit from surveillance
European Society for Medical Oncology (ESMO)¹¹	- Consider EGD surveillance every 1–3 years in high risk subsets of Lynch syndrome carriers
	- Test all Lynch syndrome carriers for H. pylori
American Society of Clinical Oncology (ASCO)¹²	- Consider EGD surveillance every 1–3 years in high risk subsets of Lynch syndrome carriers
	- Test all Lynch syndrome carriers for H. pylori
European Hereditary Tumour Group (EHTG; formerly the Mallorca Group)¹³	- Consider EGD surveillance in Lynch syndrome carriers from countries with a high background incidence of gastric cancer (Korea and Japan)
	- Test all Lynch syndrome carriers for H. pylori
European Society of Digestive Oncology (ESDO)¹⁴	- Perform EGD surveillance every 1–2 years in all Lynch syndrome carriers, beginning no later than age 30
	- Test all Lynch syndrome carriers for H. pylori

Abbreviations: EGD, esophagogastroduodenoscopy