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. 2019 Dec 31;19(2):1418–1426. doi: 10.3892/ol.2019.11246

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — miRNA-608 induces apoptosis in pancreatic cancer cell lines. (A and E) miRNA-608 was overexpressed in the (A) Panc-1 and (E) Bxpc-3 cell lines, and apoptosis was detected using flow cytometry. Transfection was confirmed in both the Panc-1 and Bxpc-3 cell lines. (B, C, F and G) Compared with the NC group, the (B and F) miRNA-608 mimic group had a significantly higher level of apoptosis in both Panc-1 and Bxpc-3 cell lines. (C and G) The statistical results of flow cytometry in the Panc-1 cell line. (D and H) Compared with the NC group, the miRNA-608 mimics group had a significantly higher level of apoptosis in both Bxpc-3 and panc-1 cell lines. Statistical results of flow cytometry in the Panc-1 and Bxpc-3 cell lines. **P<0.01, ***P<0.001 and ****P<0.0001. miRNA, microRNA; NC, negative control.