TABLE 1:
Localization of BH peaks in the tails of Dictyostelium and human myosin 1s.
| Myosin | Tail length | Name of BH peak | Location | Sequence |
|---|---|---|---|---|
| Dictyostelium | ||||
| DdMyo1A | Short | BH | β3/β4 | (858) KGDSWFAI (865) |
| DdMyo1B | Long | BH | β3/β4 | (802) KKVLVHTLIR (811) |
| DdMyo1C | Long | BH | β3/β4 | (837) TKQAIYLIKLKQKKNLAT (854) |
| BH-N | α4/α5 | (775) NRFSMI (780) | ||
| DdMyo1D | Long | BH | β3/β4 | (804) KRPWIYVQKRR (814) |
| DdMyo1E | Short | BH-N | α4/α5 | (804) YDIFHGKKKWDF (815) |
| DdMyo1F | Short | BH-N | α4/α5 | (871) RKKEWDCR (878) |
| BH | β3/β4 | (947) KYTQKKVGL (955) | ||
| Human | ||||
| HsMyo1A | Short | BH-N | α3 | (830) KRF (832) |
| BH | β1/β2 | (909) T | ||
| HsMyo1B | Short | BH-N | α3 | (915) KRIFHLWRCKKYRDQ (929) |
| HsMyo1C | Short | BH | β1/β2 | (894) DRKGYKPR (901) |
| HsMyo1D | Short | BH | β1 | (856) NVLFSCH (862) |
| HsMyo1E | Long | β1/β2 | (777) FKGVKRDLLLT (787) | |
| HsMyo1F | Long | BH | β1/β2 | (773) RRFKPIKRDLI (783) |
| BH-C | ? | (927) RKGMAKGKPR (936) | ||
| HsMyo1G | Short | BH | β1/β2 | (876) RKVNRFHKIR (885) |
| HsMyo1H | Short | BH | β1/β2 | (887) KYDRKGFKARQ (899) |
The positions of BH peaks were defined by comparing BH plots of myosins (Supplemental Figures S1 and S2) to their sequence alignments (Figures 1 and 2 and Supplemental Figure S3). BH sites are defined as amino acid residues with BH score higher than 0.6 but nine additional residues on both sides contribute to their appearance (Brzeska et al., 2010).