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. 2019 Nov 15;2(4):86. doi: 10.3390/mps2040086

Figure 2.

Figure 2

Sequential slides of human prostate tissue exhibiting cancer (Ca) invading into normal glands and high-grade prostatic intraepithelial neoplasia (HGPIN). There is an aggressive carcinoma invading glandular structures that have retained normal basal cells. The retained basal cells are positive for HMWCK + p63 (A) (grey arrowheads), positive for phosphatase tensin homolog (PTEN) (B) (black arrows), and negative for ETS-Related Gene (ERG) (C) (green arrowheads). The cancer is negative for HMWCK + p63 (A) (red arrowheads), PTEN (B) (red arrows), but positive for ERG (C) (black arrowheads). [10× magnification].