Table 2.
Assessment of pain and use of analgesics
| AC | P-NAC | S-NAC | p-value | |
|---|---|---|---|---|
| Number of patients, n (%) | 746 (86.6) | 25 (2.9) | 90 (10.5) | |
| Assessment of pain | ||||
| Any, n (%), documented by nurses | 741 (99.5) | 25 (100.0) | 89 (98.9) | n.s. |
| Any, n (%), documented by physicians | 161 (21.6) | 13 (52.0) | 57 (63.3) | < 0.001ab |
| NRS, n (%) | 738 (99.1) | 25 (100.0) | 85 (94.4) | < 0.012b |
| NRS, frequency, n per day (SD) | 2.44 (1.10) | 2.02 (1.33) | 1.68 (0.96) | n.s. |
| Pain prevalence | ||||
| Total, n (%) | 353 (47.3) | 11 (44.0) | 38 (42.2) | n.s. |
| Headache, n (%) | 188 (25.2) | 4 (16.0) | 10 (11.1) | 0.008b |
| Musculoskeletal pain, n (%) | 82 (11.0) | 1 (4.0) | 13 (14.4) | n.s. |
| Chronic pain syndrome, n (%) | 36 (4.8) | 0 (0.0) | 1 (1.1) | n.s. |
| Not specified, n (%) | 199 (26.7) | 7 (28.0) | 26 (28.9) | n.s. |
| Use of analgesics | ||||
| Any analgesic, n (%) | 363 (48.7) | 19 (76.0) | 70 (77.8) | < 0.001ab |
| Opioid, n (%) | 54 (7.2) | 5 (20.0) | 16 (17.8) | 0.001ab |
| Non-Opioid, n (%) | 278 (37.3) | 11 (44.0) | 56 (62.2) | < 0.001b |
| Co-analgesic, n (%) | 165 (22.1) | 13 (52.0) | 21 (23.3) | 0.002ac |
| Indication | ||||
| Acute or chronic pain, n (%) | 245 (32.8) | 3 (12.0) | 22 (24.4) | 0.029a |
| Prophylactic treatment, n (%) | 3 (0.4) | 5 (20.0) | 13 (14.4) | < 0.001ab |
| Not documented, n (%) | 64 (8.6) | 5 (20.0) | 18 (20.0) | 0.001b |
| Other, n (%) | 148 (19.8) | 15 (60.0) | 43 (47.8) | 0.000ab |
| Documented response to treatment, n/n (%) | 120/245 (49.0) | 1/3 (33.3) | 2/22 (9.1) | < 0.001b |
a, significant group difference AC vs P-NAC
b, significant group difference AC vs S-NAC
c, significant group difference P-NAC vs S-NAC