Table 3.
Mortality, cause of death, and in-hospital outcomes
| Standard protocol-based cohort (N = 70) | Lung rescue team cohort (N = 50) | Pa | Hazard ratio (CI 95%)a | |
|---|---|---|---|---|
| ICU mortality, n (%) | 24/70 (34) | 9/50 (18) | 0.004 | 0.29 (0.12–0.67) |
| Hospital mortality, n (%) | 29/70 (41) | 9/50 (18) | < 0.001 | 0.22 (0.10–0.51) |
| 28-day mortality, n (%) | 22/70 (31) | 8/50 (16) | 0.001 | 0.31 (0.13–0.78) |
| 3-month mortality, n (%) | 29/70 (41) | 11/50 (22) | 0.006 | 0.35 (0.16–0.74) |
| 6-month mortality, n (%) | 29/70 (41) | 11/50 (22) | 0.006 | 0.35 (0.16–0.74) |
| 1-year mortality, n (%) | 29/70 (41) | 11/50 (22) | 0.006 | 0.35 (0.16–0.74) |
| Cause of death | ||||
| Multi-organ failure | 27/29 | 7/11 | ||
| Brain injury/advanced cancer | 2/29 | 4/11 | ||
| ICU length of stay, days , mean (CI 95%) | 13 (9–16) | 17 (14–20) | < 0.001 | |
| Days not in ICU at day 28, days, mean (CI 95%)b | 12 (9–14) | 11 (8–13) | 0.413 | |
| Hospital length of stay, days, mean (CI 95%) | 19 (15–23) | 28 (23–33) | < 0.001 | |
| Days not in hospital at day 28, days, mean (CI 95%)b | 7 (5–9) | 5 (3–7) | 0.121 | |
| Ventilation-free days, days, mean (CI 95%)b | 14 (11–16) | 15 (12–18) | 0.859 | |
| Reintubation, n (%) | 12/70 (17) | 8/50 (16) | 0.868 | |
| Tracheostomy, n (%) | 11/70 (16) | 14/50 (28) | 0.061 | |
| AKI, n (%) | 37/70 (52) | 26/50 (54) | 0.902 | |
| RRT, n (%) | 16/70 (23) | 12/50 (24) | 0.884 | |
Abbreviations: CI confidence interval, ICU intensive care unit, AKI acute kidney injury, RRT renal replacement therapy
aP values and hazard ratios for mortality calculated after correction for common ICU confounding factors (APACHE, age, BMI, PaO2/FiO2)
bIf in-hospital death occurred before day 29, the ventilation-free days, the days not in ICU at day 28, and the days not in hospital at day 28 were considered to be zero