Table 5.
The results of the linear mixed effect models of the activity of phagocytic cells, and their respective means and standard deviations, in 10 dogs fed daily (BID), and intermittently fasted on a low fat (IF LF) and a high fat diet (LF HF) in a Latin Square design.
| Outcome | Diet | Mean | Standard deviation | Fixed effect | Estimate | Standard error | P-value |
|---|---|---|---|---|---|---|---|
| Lymphocyte oxidation | BID | 45.3 | 18.4 | (Intercept) | 30.6 | 25.3 | |
| (%) | IF LF | 35.0 | 19.3 | Diet IF LF | −10.7 | 3.9 | 0.008 |
| IF HF | 43.1 | 17.1 | |||||
| Monocyte phag+/ox+ | BID | 64.9 | 20.0 | (Intercept) | 72.3 | 28.6 | |
| MFI for oxidation | IF LF | 57.9 | 25.8 | Diet IF LF | −7.6 | 4.0 | 0.06 |
| IF HF | 66.0 | 23.5 | |||||
| Neutrophil oxidation | BID | 75.8 | 17.6 | (Intercept) | 73.6 | 23.3 | |
| (%) | IF LF | 71.0 | 17.6 | Diet IF LF | −4.9 | 2.2 | 0.02 |
| IF HF | 75.9 | 16.8 | |||||
| Neutrophil phag+/ox+ | BID | 74.7 | 18.1 | (Intercept) | 67.9 | 23.2 | |
| (%) | IF LF | 69.9 | 17.6 | Day | −0.8 | 0.4 | 0.04 |
| IF HF | 74.4 | 16.4 | Diet IF LF | −5.0 | 2.2 | 0.03 |
Only independent variables with a P ≤ 0.1 are shown. The percentage is the number of cells that have undergone either phagocytosis and/or oxidative burst. Mean florescence intensity (MFI) of oxidation is proportional to the degree in which oxidation has occurred.