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. 2020 Jan 3;2020:3856242. doi: 10.1155/2020/3856242

Table 3.

Estimated prevalence of post-MI patients eligible to PCSK9 inhibitors according to the EAS/ESC and AIFA criteria.

EAS/ESC criteria (n = 2977) N %
Statin and/or ezetimibe + noDM + LDL-C >140 mg/dl 130 4,37
Statins and/or ezetimibe + DM + LDL-C >100 mg/dl 163 5.48

AIFA criteria (n = 2029)

High intensity statins and ezetimbe + age ≤80 yrs + eCrCl ≥ 30 ml/min + LDL-C >100 mg/dl 450 22.2

DM, diabetes mellitus; eCrCl, estimated creatinine clearance, LDL-C, low density lipoprotein cholesterol.

These groups included patients receiving any statins at any dosage. Monoterapy with ezetimibe has been taken as a proxy of statin intolerance.

High intensity statins have been considered atorvastatin 40–80 mg /day or rosuvastatin 20–40 mg/day. Monoterapy with ezetimibe has been taken as a proxy of statin intolerance.