HOXA11-AS promotes keloid-related phenotypes via miR-124-3p/TGFβR1-induced activation of PI3K/Akt signaling.
(a) qRT-PCR assay was performed to examine the expression of TGFβR1. (b) and (d) Cells apoptosis was examined by flow cytometry. (c) and (e) The angiogenesis of HUVECs were detected by tube formation assay. (f) Western blot analysis of the expression of TGFβR1, Bax, Bcl-2, p-PI3K, PI3K, p-Akt, Akt. *P < 0.05, **P < 0.01.