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. 2019 Dec 26;19(2):233–245. doi: 10.1080/15384101.2019.1707456

Figure 6.

Figure 6.

Effect of HOXB5 on PC cell growth and metastasis in vivo. (a) Representative tumor images in capan-2/scramble, capan-2/HOXB5, capan-2/miR-6723, and capan-2/HOXB5 + miR-6723-ASO groups (n = 6 per group). (b) Tumor volume follow days; HOXB5 and miR-6723 overexpression promote tumor growth. Quantification of fluorescence from metastatic tumors (P < 0.01). (c) H&E staining of metastatic tumors in lung tissues and node counts; HOXB5 and miR-6723 promoted lung metastasis. (d) Kaplan–Meier survival analysis of mice in different groups. (e) IHC staining of tumor samples and gray analysis of the positive area for the detection of progression markers for each group.