Figure 3.

MiR-155-5p regulates the production of type I IFNs. miR-155-5p mimics and its inhibitor were transfected into RD cells for 24 h, and then the cells were infected with EV71 (MOI = 1) for 24 h. (a, b) The expressions of IFN-α/β were measured by ELISA. (c–f) Expressions of IFN-stimulated genes (ISGs), ISG15, OAS, MxA and PKR were measured by qRT-PCR. Data are the mean ± S.D. (n = 3) of one representative experiment. *p  <  0.05, **p  <  0.01 vs. control group; ##p  <  0.01 vs. mimics NC group; &&p  <  0.01 vs. inhibitor NC group.