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Results of differential methylation benchmark.
| Approach # | Platform | Estimates | Pooling of methylation levels | Pooling of p-values | Model | c-statistic |
|---|---|---|---|---|---|---|
| I | EPIC | βA | No | No | Logistic regression | 0.761 |
| II | TruSeq | βC | Yes | No | Weighted logistic regression | 0.663 |
| III | TruSeq | βR | No | No (reference loci only) | Weighted logistic regression | 0.647 |
| IV | TruSeq | βR | No | Yes | Weighted logistic regression | 0.675 |
| V | TruSeq | βS | Yes | Yes | Linear regression | 0.586 |
