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. 2019 Dec 13;32:136–147. doi: 10.1016/j.molmet.2019.12.003

Figure 1.

Figure 1

Adipocyte-specific ablation of mTORC1 elevates plasma lipids prior to lipodystrophy. (A) Western blotting for Raptor in IWAT, EWAT, BAT, and liver. Numbers indicate relative density normalized to β-actin. (B) Western blotting of downstream mTORC1 substrates in IWAT, EWAT, and BAT of RaptoraKO and Raptorfl/fl littermates. (C) Body and (D) tissue weights with age of male RaptoraKO mice compared to controls (male, n = 3–11). (E) Tissue weights and (F) random fed plasma lipid parameters of 10-week-old RaptoraKO mice (n = 6–9). Data presented as mean ± s.e.m. *p < 0.05, **p < 0.01, ***p < 0.001.