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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Bioorg Med Chem. 2019 Sep 13;27(22):115121. doi: 10.1016/j.bmc.2019.115121

Figure 2. A-site RNA secondary structures.

Figure 2.

RNA duplexes representing (A) E. coli (wt-bac), (B) wild-type human mitoribosomal (wt-mt), and (C) A1555G mutant human mitoribosomal (mut-mt) A-site sequences are shown (the A-site region is boxed). The nucleotides that are different in either wild-type or mutant mt sequences compared to the E. coli sequence are shown in red. The point mutation in the mut-mt sequence is shown in green. The rRNA numbering systems for E. coli and human mitochondria are used. The black dots (•) represent non-Watson-Crick base pairs and F is a 5′-fluorescein tag.