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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Cell Rep. 2019 Dec 10;29(11):3751–3765.e5. doi: 10.1016/j.celrep.2019.11.026

Figure 7. Correlation of Isoform Differential Regulation at Transcript and Protein Levels.

Figure 7.

Scatterplots showing differential expression (logFC) of isoforms at transcript (y axis) versus protein (x axis) levels during iPSC-CM differentiation for noncanonical junction sequences only (A) and all canonical SwissProt unique sequences (B) that were quantified in both RNA-seq and MS and found to be differentially regulated. Protein and transcript isoform logFC show robust positive correlation (Pearson’s r, 0.57–0.74 noncanonical isoforms; 0.52–0.57 canonical). Blue line, best-fit linear regression; red dashed line, unity.