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Lamellar and non-lamellar lipid-based films and particles for delivery of small molecules. Top left: supported 1D-lamellar siRNA complex. Reprinted by permission of the publisher (John Wiley and Sons) [13]. Top right: liposome-siRNA complex. Bottom left: supported 3D bicontinuous cubic lipid film loaded with siRNA. Reprinted by permission of the publisher (John Wiley and Sons) [13]. Bottom right: cubosome-siRNA complex. Reprinted with permission from [19]. Copyright 2018 American Chemical Society.