Table 5. mtDNA synonymous variations of OXPHOS complex-I subunits and complex-III encoding genes.
Synonymous changes | Gene | Amino acid change | Transition/ Transversion | Frequency (%) | X2 score | p-value |
---|---|---|---|---|---|---|
4769 A>G | ND2 | M-M | Transition | 9 | 131.2331 | <0.05 |
10400 C>T | ND3 | T-T | Transition | 43 | 15.7051 | 0.000074 |
10873 T>C | ND4 | P-P | Transition | 25 | 52.0252 | <0.05 |
11083 A>G | ND4 | M-M | Transition | 2 | 52.0252 | <0.05 |
11467 A>G | ND4 | L-L | Transition | 5 | 1.8018 | 0.179495 |
11812 A>G | ND4 | L-L | Transition | 2 | 5.6738 | 0.017221 |
12007 G>A | ND5 | W-W | Transition | 7 | 0.5786 | 0.446865 |
12372 G>A | ND5 | L-L | Transition | 2 | 5.6738 | 0.017221 |
12705 C>T | ND5 | I-I | Transition | 7 | 108.4122 | <0.05 |
14905 G>A | CYTB | M-M | Transition | 2 | 5.6738 | 0.017221 |
15043 G>A | CYTB | G-G | Transition | 16 | 82.0513 | <0.05 |
15301 G>A | CYTB | L-L | Transition | 32 | 46.7532 | <0.05 |
11251 A>G | CYTB | L-L | Transition | 2 | 5.6738 | 0.017221 |