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. 2019 Dec 5;4(23):e133103. doi: 10.1172/jci.insight.133103

Figure 2. Single-cell RNA-seq analysis of NK cells using integrated data from 5 patients.

Figure 2

(A) NK cell populations in blood (left) and metastases (right) analyzed by scRNA-seq using merged data from 5 patients (CD129.2, CY155, CY158, CY160, and CY164). NK cell clusters in blood and metastases were visualized using UMAP plots. The percentage of NK cells in each cluster and key differentially expressed genes for each cluster are indicated. (B) mRNA transcripts for selected genes in blood (top) and tumor-infiltrating (bottom) NK cell populations were visualized using UMAP plots. The intensity of the blue color indicates the level of expression for indicated genes in individual cells and is scaled separately between blood and tumor-infiltrating NK cells within the integrated data set from 5 patients.