Figure 3. CMV+ infants are at increased risk of developing TB disease.
(A) We saw a higher proportion of case (red) infants among CMV+ (n = 14 of 32) when compared with CMV– infants (n = 35 of 140), and there was no significant enrichment for cases among EBV+ infants (n = 3 of 7 compared with n = 46 of 163), although infants positive for either CMV or EBV (B) were at increased risk (n = 17 of 39 compared with 32 of 131). (C) CMV+ TB case infants (red triangles, n = 14) developed TB disease earlier in follow-up when compared with CMV– infants (red circles, n = 35), and (D) TB case infants positive for either CMV or EBV (red triangles, n = 17) developed TB disease earlier than CMV–/EBV– infants (red circles, n = 32).