Table 2. Estimated parameters for UDCA response in the model derivation cohort: results from the logistic model based on baseline characteristics (original cohort n=2703, used observations n=2640, missing 2.3%).
Variable | Parameter Estimate | Standard error | Wald statistic | p-value |
---|---|---|---|---|
Intercept | 0.774 | 0.425 | ||
Ln(ALPdiag (xULN)) | -2.730 | 0.138 | -19.765 | <0.0001 |
1/√TBdiag (xULN)) | 0.600 | 0.165 | 3.637 | 0.0003 |
Ln(TAdiag (xULN)) | 0.350 | 0.108 | 3.236 | 0.0012 |
Age (years) | 0.028 | 0.006 | 5.074 | <0.0001 |
Treatment time-lag (years) | -0.154 | 0.035 | -4.362 | <0.0001 |
ΔALP (xULN) | -0.557 | 0.073 | -7.588 | <0.0001 |
Abbreviations: Ln, natural logarithm