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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Lancet Gastroenterol Hepatol. 2018 Jul 13;3(9):626–634. doi: 10.1016/S2468-1253(18)30163-8

Table 2. Estimated parameters for UDCA response in the model derivation cohort: results from the logistic model based on baseline characteristics (original cohort n=2703, used observations n=2640, missing 2.3%).

Variable Parameter Estimate Standard error Wald statistic p-value
Intercept 0.774 0.425
Ln(ALPdiag (xULN)) -2.730 0.138 -19.765 <0.0001
1/√TBdiag (xULN)) 0.600 0.165 3.637 0.0003
Ln(TAdiag (xULN)) 0.350 0.108 3.236 0.0012
Age (years) 0.028 0.006 5.074 <0.0001
Treatment time-lag (years) -0.154 0.035 -4.362 <0.0001
ΔALP (xULN) -0.557 0.073 -7.588 <0.0001

Abbreviations: Ln, natural logarithm