Fig. 1.

EBV carriage is associated with the accumulation of 8-oxodG. a Pairs of EBV-negative and -positive B-cell lymphoma lines were subjected to immunofluorescence staining with antibody against 8-oxodG (green) and the nuclei were stained with DAPI (blue). Representative micrographs illustrating the expression of 8-oxodG in the BJAB and BL41 cell pairs. b Quantification of 8-oxodG specific fluorescence in three independent experiments. Relative FL intensity is the ratio between FL intensity in EBV positive and negative cells. c 8-oxodG fluorescence was assayed in pairs of EBV-negative and -positive epithelial cell lines. Representative micrographs illustrating the expression of 8-oxodG (red). The nuclei were stained with DAPI (blue). d Quantification of the 8-oxodG specific fluorescence in three independent experiments. Significance was calculated using Student T-test, *P < 0.05, **P < 0.01