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. 2019 Sep 19;39(3):677–689. doi: 10.1038/s41388-019-1005-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Characterizing diverse chromatin states of network motifs. a Significant association between chromatin state compositions and total eighteen types of motifs in four cell lines. Different colors indicate fifteen chromatin states used in this study from Ernst et al. b The numbers of chromatin state compositions associated with a particular motif. c Six kinds of enriched chromatin state-modified C1-FFL motifs in GM12878. The colors of nodes indicate the chromatin states of corresponding genes