Skip to main content
. 2020 Jan 9;10:2926. doi: 10.3389/fimmu.2019.02926

Figure 4.

Figure 4

β-diversity of gut microbiota. Distance boxplots weighted_unifrac (A) and unweighted unifrac (B): I—All within the description, II—All between description, III—caspase-1/11−/− SFD vs. caspase-1/11−/− SFD, IV—caspase-1/11−/− HFD vs. caspase-1/11−/− HFD, and V—caspase-1/11−/− SFD vs. caspase-1/11−/− HFD. (C) PCoA plot weighted_unifrac and (D) PCoA plot unweighted_unifrac, blue: caspase-1/11−/−SFD, red: caspase-1/11−/− HFD. Distance boxplots weighted_unifrac (E) and unweighted unifrac (F): I—All within the description, II—All between description, III—caspase-1/11−/− HFD vs. caspase-1/11−/− HFD, IV—WT HFD vs. WT HFD, and V—caspase-1/11−/− HFD vs. WT HFD. (G) PCoA plot weighted_unifrac and (H) PCoA plot unweighted_unifrac, purple: WT HFD, red: caspase-1/11−/− HFD. The tests of significance were performed using a two-sided Student's two-sample t test, the non-parametric p-values were calculated with Bonferroni correction. p-values for comparisons of Distance boxplots (A): I vs. II p = 0.09, I vs. III p = 1, I vs. VI p = 1, I vs. V p = 0.05, II vs. III p = 0.07, II vs. IV p = 0.6, II vs. V p = 1, III vs. IV p = 1, III vs. V p = 0.12, and IV vs. V p = 0.54; (B): I vs. II p = 0.01, I vs. III p = 0.39, I vs. VI p = 0.89, I vs. V p = 0.01, II vs. III p = 0.01, II vs. IV p = 1, II vs. V p = 1, III vs. IV p = 0.03, III vs. V p = 0.01, and IV vs. V p = 1; (E): I vs. II p = 0.010, I vs. III p = 1, I vs. VI p = 1, I vs. V p = 0.01, II vs. III p = 0.1, II vs. IV p = 0.01, II vs. V p = 1, III vs. IV p = 1, III vs. V p = 0.15, and IV vs. V p = 0.01; (F): I vs. II p = 0.01, I vs. III p = 1, I vs. VI p = 1, I vs. V p = 0.01, II vs. III p = 0.01, II vs. IV p = 0.01, II vs. V p = 1, III vs. IV p = 1, III vs. V p = 0.01, and IV vs. V p = 0.01.