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. 2020 Jan 15;10:321. doi: 10.1038/s41598-019-56947-1

Table 3.

Diagnostic performance of AAT-A3F and other biomarkers for predicting NASH.

AUC Cut-off Sensitivity (%) Specificity (%) PPV (%) NPV (%)
AAT-A3F 0.687 14.1 38 95 90 54
cCK18 0.655 977 42 86 79 53
M2BPGi 0.749 0.69 77 69 77 69
FIB4 index 0.700 1.44 73 67 74 66
APRI 0.672 0.86 50 81 77 55

Abbreviations: AUC, area under the curve; NPV, negative predictive value; PPV, positive predictive value; NASH: non-alcoholic steatohepatitis