Table 1.
Baseline characteristics of HCM patients.
| No HTN (n = 172) | HTN (n = 90) | P-value | |
|---|---|---|---|
| Demographics | |||
| Age at HCM diagnosis | 47 ± 16.2 | 55 ± 12.5 | <0.001 |
| Male gender | 101 (59%) | 61 (68%) | >0.05 |
| Medical history and cardiovascular risk factors | |||
| Hyperlipidaemia | 35 (22%) | 31 (38%) | <0.01 |
| Current smoking | 35 (22%) | 21 (26%) | >0.1 |
| Coronary artery disease | 35 (22%) | 27 (33%) | >0.05 |
| TIA | 3 (2%) | 7 (8%) | <0.05 |
| Chronic obstruction pulmonary disease | 3 (2%) | 6 (7%) | <0.05 |
| Chronic renal failure | 1 (0.6%) | 4 (5%) | <0.05 |
| History of VT | 21 (12%) | 8 (9%) | >0.05 |
| Clinical features | |||
| Angina pectoris | 76 (44%) | 43 (48%) | >0.9 |
| Personal history syncope | 37 (22%) | 7 (8%) | <0.01 |
| Atrial fibrillation | 50 (29%) | 31 (34%) | >0.05 |
| Family history HCM | 27 (16%) | 7 (8%) | >0.05 |
| Family history sudden cardiac death | 18 (10%) | 3 (3%) | <0.05 |
| Device implantation | |||
| Permanent pacemaker | 12 (7%) | 8 (9%) | >0.05 |
| Implanted defibrillator | 6 (3%) | 1 (1%) | >0.05 |
| Death cases in 5-year follow-up | 7 (4%) | 8 (9%) | >0.05 |
| Causes of death | |||
| Cardiac related deatha | 5 (71%) | 3 (38%) | >0.05 |
| Non-cardiac related deathb | 2 (29%) | 5 (62%) | |
Categorical parameters are presented as n(%). Continuous variables are expressed as mean and standard deviation. HCM, hypertrophic cardiomyopathy; TIA, transient ischaemic attack; VT, ventricular tachycardia. aAcute heart failure, arrhythmia, myocardial ischemia. bInfection, stroke, chronic renal failure and chronic obstruction pulmonary disease.