TABLE 2.
Descriptive statistics by sex.
| Variable | Female (n = 269) | Male (n = 268) | p-value |
| Age (years) | 58.7 (4.3) | 58.7 (4.2) | ns |
| Education (years) | 15.1 (2.2) | 15.3 (2.2) | ns |
| Educ-occ composite | 12.8 (2.3) | 13.3 (2.1) | 0.0195 |
| Global cognition (Z-score) | 0.83 (076) | 0.68 (0.77) | 0.0297 |
| Memory (Z-score) | 0.78 (0.84) | 0.45 (0.88) | <0.0001 |
| Attention (Z-score) | 0.79 (0.75) | 0.53 (0.70) | <0.0001 |
| Language (Z-score) | 0.60 (0.89) | 0.39 (0.84) | 0.0049 |
| Visuospatial (Z-score) | 0.45 (0.80) | 0.78 (0.85) | <0.0001 |
| Genu corpus callosum (FA) | 0.62 (0.04) | 0.63 (0.04) | 0.0269 |
| Posterior cingulate (FDG) | 2.00 (0.16) | 1.92 (0.16) | <0.0001 |
| AD ROI (Thick) | 2.98 (0.12) | 2.98 (0.12) | ns |
| Superior parietal (Thick) | 2.06 (0.12) | 2.03 (0.13) | 0.0013 |
| Intracranial volume | 1381.3 (112.9) | 1596.1 (128.4) | <0.0001 |
| CMC | 1.0 (1.1) | 1.3 (1.2) | 0.0003 |
| BMI | 29.3 (6.6) | 29.3 (4.5) | ns |
| HbA1c | 5.5 (0.6) | 5.6 (0.8) | ns |
| BDI score | 4.1 (4.7) | 4.7 (4.9) | ns |
| Physical activity | 6.6 (4.3) | 6.8 (4.8) | ns |
| Cognitive activity | 23.3 (8.6) | 18.9 (8.1) | <0.0001 |
| Smoke: No/Yes (%) | 170(63)/99(37) | 154(57)/114(43) | ns |
| CAGE > 2: No/Yes (%) | 255(94)/14(6) | 245(91)/23(9) | ns |
| APOE4: −/+ (%) | 187(72)/74(28) | 183(70)/78(30) | ns |
Mean (Standard Deviation) for continuous variables. Count (%) for dichotomous variables. p-values for t-test and chi-square of differences in group means.