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. 2020 Jan 9;10:1292. doi: 10.3389/fgene.2019.01292

Table 1.

Description of the patient cohort. p-values were computed using Wilcoxon tests (quantitative values) or Fisher tests (percentages).

Control group (n  =  8) IUGR group (n  =  28) p
Maternal data Age (years) 35.4 ± 3.9 8 29.1 ± 5.9 28 0.006
BMI before pregnancy (kg/m2) 23.7 ± 7.0 8 25.1 ± 7.9 28 N.S.
Tobacco consumption Before pregnancy 0 (0.0%) 8 2 (7.1%) 28 N.S.
During pregnancy 0 (0.0%) 8 9 (32.1%) 28 N.S.
Ethnic group European 7 (87.5%) 8 26 (92.9%) 28 N.S.
North African 1 (12.5%) 8 2 (7.1%) 28 N.S.
Obstetric data Gestity 4.0 ± 2.1 8 2.5 ± 1.9 28 0.03
Parity 2.6 ± 1.3 8 1.4 ± 0.9 28 0.005
Weight gain (kg) 10.5 ± 10.5 8 9.1 ± 6.4 24 N.S.
Type of delivery Vaginal delivery 0 (0%) 8 5 (17.9%) 28 N.S.
C-section 8 (100%) 8 23 (82.1%) 28 N.S.
Pathology IUGR 0 (0%) 8 16 (57.1%) 28 N/A
IUGR + PE 0 (0%) 8 12 (42.9%) 28 N/A
Newborn data Gestational age (week) 38.7 ± 0.7 8 34.0 ± 3.9 28 <0.001
Gender Boy 4 (50.0%) 8 9 (32.1%) 28 N.S.
Girl 4 (50.0%) 8 19 (67.9%) 28 N.S.
Birth weight (Z-score) −0.07 ± 0.89 8 −2.02 ± 0.75 28 <0.001
(g) 3346 ± 444 8 1,524 ± 664 28 <0.001
Birth size (Z-score) −0.47 ± 0.74 7 −1.90 ± 0.80 26 <0.001
Birth size (cm) 49.2 ± 1.8 7 39.2 ± 5.2 26 <0.001
Head circumference at birth (Z-score) 0.22 ± 0.49 7 −1.30 ± 0.86 27 <0.001
Head circumference at birth (cm) 34.6 ± 0.9 7 29.0 ± 3.4 27 <0.001
APGAR at 5 min 9.88 ± 0.35 8 9.11 ± 2.08 28 N.S.
Resuscitation at birth 0 (0%) 8 12 (42.9%) 28 0.03
NICU 0 (0%) 8 18 (64.3%) 28 0.003

BMI, body mass index; PE, pre-eclampsia; NICU, neonatal intensive care unit; N.S., non-significant versus α = 0.05; N/A, not applicable.