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. 2020 Jan 9;10:1538. doi: 10.3389/fphar.2019.01538

Figure 4.

Figure 4

NSA improves the motor function and spinal edema of SCI-mice. The behavioral performances in mice with SCI or treatment with NSA (L: 1 mg/kg, M: 5 mg/kg, H: 10 mg/kg) were shown at 1, 2, 3, 7, 14, 21, and 28 days following surgery. (A) pair forepaws were measured. (B) Daily measurement of the BMS scores. (C) Dry and wet specific gravity method was used to measure spinal edema at 3 days post-SCI. Data are reported as the mean ± SEM, n = 9. & p < 0.05, vs. the sham group. *p < 0.05, vs. the SCI+Vehicle group. # p < 0.05, vs. the NSA-L group. A and B: Data were analyzed by two-way ANOVA followed by Tukey’s multiple comparison test. C: Data were analyzed by one-way ANOVA followed by Tukey’s multiple comparison test. SCI, spinal cord injury; NSA, necrosulfonamide; BMS, basso mouse scale.