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. 2020 Jan 9;10:3076. doi: 10.3389/fmicb.2019.03076

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Copyright © 2020 Lee, Teng, DiLorenzo, Weppelmann and Jeong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genetic environment of β-lactamase genes in representative isolates Linear map shows the regions surrounding β-lactamase genes in each isolate. Isolates encode CMY-2 (A), CTX-M-1 (B), CTX-M-27 (C), and CTX-M-32, CTX-M-15, and CTX-M-55 (D) are presented. Only isolates showing different structures were included, and sequence homology was compared if the isolates carried same β-lactamase gene. Gradient-color between linear maps indicates the similarity between isolates. β-lactamase genes, other virulence factors, insertion sequences, conjugal transfer genes, and general CDS are indicated by red, pink, yellow, brown, and green arrows, respectively.