Table 2.
Univariate and multivariate analysis for DFS in patients with FIGO IIIC1 (2018).
| Variables | No. of patients 325 | 3-year DFS | Univariate analysis (Log-rank test) |
Multivariate analysis (Cox proportional hazard model) | |
|---|---|---|---|---|---|
| P | HR (95%CI) | P | |||
| Tumor size | |||||
| ≥4 cm | 240 (73.9%) | 57.6% | 0.001 | 2.00 (1.13–3.57) | 0.018 |
| <4 cm | 80 (24.6%) | 84.5% | |||
| uncertainty | 5 (1.5%) | ||||
| Parametrial infiltration | |||||
| yes | 265 (81.5%) | 65.1% | 0.589 | ||
| no | 60 (18.5%) | 69.4% | |||
|
Invasion of pelvic wall | |||||
| yes | 60 (18.5%) | 51.1% | <0.001 | 0.65 (0.40–1.05) | 0.078 |
| no | 265 (81.5%) | 69.9% | |||
| Invasion of the lower third of vagina | |||||
| Yes | 11 (3.4%) | 45.5% | 0.084 | ||
| no | 314 (96.6%) | 69.1% | |||
| Pelvic lymph node metastasis | |||||
| bilateral | 145 (44.6%) | 54.6% | 0.005 | 1.06 (0.57–1.97) | 0.855 |
| unilateral | 135 (41.5%) | 72.4% | |||
| uncertainty | 45 (13.9%) | ||||
| Common iliac lymph node metastasis | |||||
| yes | 49 (15.1%) | 57.8% | 0.187 | ||
| no | 231 (71.1%) | 65.3% | |||
| uncertainty | 45 (13.8%) | ||||
| Number of PLNM | |||||
| ≥2 | 171 (52.6%) | 55.8% | <0.001 | 2.10 (1.04–4.24) | 0.039 |
| <2 | 109 (33.5%) | 79.6% | |||
| uncertainty | 45 (13.9%) | ||||
Abbreviations: FIGO = International Federation of Gynecology and Obstetrics, HR = hazard ratio, DFS = disease free survival, PLNM = Pelvic lymph nodes metastasis.