Table 1.

Search strategy and inclusion/exclusion criteria based on PICO.

Databases	Search terms	PICO	Inclusion criteria	Exclusion criteria
PubMed	Inflammation Exercise	Population	Healthy adults (18–65 years)	Sedentary adults; adults with disease
		Intervention	Moderate exercise	No exercise intensity definition
			Intense exercise
		Comparison	Intense with moderate exercise
		Outcome	Alterations in PBMC (WBC, lymphocytes, NK cells, or NK cytolytic activity), Cytokines (IL-6, IL-8, IL-1β, TNF-α, or IL-10), CRP, or CK	No results on inflammatory markers