. 2020 Jan 15;10:378. doi: 10.1038/s41598-019-57252-7

Table 2.

Levels of some oxidative markers in the liver, kidney and spleen of male and female rats euthanized by exsanguinations following exposure to different doses of sodium pentobarbital.

Gender	Organ	Dosage (mg/Kg. body weight)	MDA (nmol/g. tissue)	GSH (mg/g. tissue)	CAT (U/g. tissue)
Female	Liver	50	5.48 ± 0.66 ^a	6.24 ± 0.88^a	0.97 ± 0.07^a
		100	6.71 ± 0.50^b	8.98 ± 0.62^b	1.12 ± 0.21^a
		150	8.43 ± 1.88^c	12.21 ± 0.25^c	1.23 ± 0.07^a
	Kidney	50	3.28 ± 0.83^a	2.34 ± 0.23^a	1.01 ± 0.15^a
		100	4.76 ± 0.54^b	3.11 ± 0.63^b	0.97 ± 0.11^a
		150	7.96 ± 0.58^b	3.29 ± 0.82^b	1.26 ± 0.05^a
	Spleen	50	4.84 ± 0.73^a	3.31 ± 0.56^a	0.65 ± 0.22^a
		100	5.99 ± 1.04^b	4.66 ± 0.35^b	0.73 ± 0.06^a
		150	6.43 ± 0.71^b	4.99 ± 0.22^b	0.85 ± 0.10^a
Male	Liver	50	4.33 ± 0.90^a	4.12 ± 0.99^a	1.10 ± 0.13^a
		100	5.99 ± 1.43^b	7.14 ± 0.43^b	1.20 ± 0.15^a
		150	7.81 ± 0.50^c	10.75 ± 0.78^c	1.29 ± 0.04^a
	Kidney	50	3.97 ± 0.57^a	2.69 ± 0.84^a	0.79 ± 0.11^a
		100	5.33 ± 0.67^b	3.12 ± 0.60^b	0.89 ± 0.08^a
		150	6.47 ± 0.59^b	3.63 ± 0.02^b	0.92 ± 0.14^a
	Spleen	50	4.80 ± 0.55^a	3.54 ± 0.62^a	0.79 ± 0.21^a
		100	5.38 ± 0.41^b	4.58 ± 0.26^b	0.96 ± 0.13^a
		150	5.67 ± 0.20^b	4.61 ± 0.69^b	1.01 ± 0.05^a
Effect of gender		Liver	P > 0.05	P > 0.05	P > 0.05
		Kidney	P > 0.05	P > 0.05	P > 0.05
		Spleen	P > 0.05	P > 0.05	P > 0.05
Effect of Dosage		Liver	P < 0.05	P < 0.05	P > 0.05
		Kidney	P < 0.05	P < 0.05	P > 0.05
		Spleen	P < 0.05	P < 0.05	P > 0.05
Interaction of gender and dosage		Liver	P > 0.05	P > 0.05	P > 0.05
		Kidney	P > 0.05	P > 0.05	P > 0.05
		Spleen	P > 0.05	P > 0.05	P > 0.05

Values are mean ± SEM (n = 6).

Values within each gender and biochemical marker, different superscripted letters indicate significantly (P < 0.05) different values.