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. 2020 Jan 15;10:311. doi: 10.1038/s41598-019-56983-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Canonical, Motility, and Cell Cycle Pathway groups and the miR548 family are predicted to be altered under 23 Pa CSS based on mRNA-miRNA interaction analysis. (A) Percent overlap and (B) cumulative absolute fold change (FC) for each pathway group. (C) Percent overlap and (D) cumulative absolute FC for each miR group based on literature relevance to GBM. Levels connected by a star (*) are statistically significant at α = 0.05. (E) Percent overlap and (F) cumulative absolute FC for each miRNA across all pathways. Letters not connected by the same letter are statistically different at α = 0.05. miRNA denoted with a hashtag (#) denotes a substitution for a miRNA included in a host gene.