Figure 8.
(A) Example images of cellular reactive oxygen species (ROS) measure after VSMCs were stretched with V0, V6, V25 or V50 in the absence or presence of AMP-PNP (AMP) or hydrogen peroxide (H2O2). (B) Box plots of ROS following the 4 different stretching patterns. For each variability, data were pulled from the control, AMP-PNP as well as H2O2 conditions. The medians are statistically different between any conditions. (C) Box plots of ROS as a function of treatment with all variabilities pulled for each treatment. All groups are statistically different from each other. (D) Box plots of efficiency defined as the ratio of mean TMRM intensity and mean ROS intensity in each VSMC following the 4 different stretching patterns. For each variability, data were pulled from the control, AMP-PNP as well as H2O2 conditions. The statistically significant differences between conditions are shown by bars under the data. (E) Box plots of efficiency as a function of treatment with all variabilities pulled for each treatment. The medians are not statistically significantly different.