Table 1.
Demographic and clinical pathologic information between NPC survivors and sporadic oral SCC patients
| NPC survivor (n=83) | Sporadic oral SCC (n=1,158) | p-value | |
|---|---|---|---|
| Age (yr) | |||
| ≥ 60 | 46 | 632 | 0.881 |
| < 60 | 37 | 526 | |
| Sex | |||
| Male | 67 | 891 | 0.428 |
| Female | 16 | 267 | |
| Drinker | |||
| Yes | 8 | 200 | 0.072 |
| No | 75 | 958 | |
| Smoker | |||
| Yes | 11 | 323 | 0.004 |
| No | 72 | 835 | |
| Tumor site | |||
| Tongue | 54 | 486 | 0.004 |
| Mouth floor | 6 | 312 | |
| Buccal | 13 | 203 | |
| Lower gingiva | 10 | 157 | |
| Tumor stage | |||
| T1+T2 | 59 | 736 | 0.167 |
| T3+T4 | 24 | 422 | |
| Disease stage | |||
| I+Ⅱ | 51 | 633 | 0.230 |
| Ⅲ+Ⅳ | 32 | 525 | |
| Node stage | |||
| N0 | 55 | 789 | 0.724 |
| N+ | 28 | 369 | |
| Differentiation | |||
| Well | 47 | 554 | 0.133 |
| Moderate | 23 | 377 | |
| Poor | 13 | 167 | |
| Unknown | 0 | 60 | |
| Perineural invasion | |||
| Positive | 23 | 130 | < 0.001 |
| Negative | 60 | 949 | |
| Unknown | 0 | 79 | |
| Lymphovascular invasion | |||
| Positive | 16 | 153 | < 0.001 |
| Negative | 67 | 955 | |
| Unknown | 0 | 50 | |
| Treatment | |||
| S | 15 | 145 | 0.235 |
| S+R | 30 | 369 | |
| S+R+C | 38 | 612 |
NPC, nasopharyngeal carcinoma; SCC, squamous cell carcinoma; S, surgery; R, radiotherapy; C, chemotherapy.