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. 2019 Apr 26;52(1):10–23. doi: 10.4143/crt.2019.145

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Copyright © 2020 by the Korean Cancer Association

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — Cathepsin C (CTSC) is frequently upregulated in hepatocellular carcinoma (HCC) and correlated with poor prognosis of HCC patients. (A) The mRNA level of CTSC in HCC specimens analyzed by GEPIA web tool. (B) Western blot assay detected CTSC expression in both HCC and normal tissues. GAPDH, glyceraldehyde 3-phosphate dehydrogenase. (C) The correlation between CTSC expression and overall survival (OS) analyzed by GEPIA. (D) The differential expression in HCC specimens upon tissue microarrays. T, tumor; N, adjacent normal liver. (E) Kaplan-Meier survival analysis of OS in 122 HCC patients upon tissue microarrays.